Zero could refer to:
- Zero (Mega Man) - A character from the Mega Man series.
- Zero (Kirby) - A character in the Kirby series.
- Zero (Bayonetta) - A demon from the Bayonetta series.
- E-100 Alpha - A robot in the Sonic the Hedgehog series, more commonly known as ZERO.
- Bomber Zero - A Bomberman in the Bomberman anime, mostly known as Zero.