(This article is about the original Dr. Mario game. You may be looking for the character himself)
Dr. Mario (video game)
Dr. Mario (NES) (NA)
Developer(s) Nintendo
Publisher(s) Nintendo
Platform(s) Nintendo Entertainment System platform icon Game Boy platform icon Satellaview platform icon Game Boy Advance platform icon Virtual Console (3DS) platform icon Virtual Console (Wii U) platform iconNintendo Switch platform icon
Genre(s) Puzzle
Soundtrack(s) Famicom Sound History Series: Mario the Music

03ESRB - E  01PEGI 3  01CERO A  01Australian Classification Board - G

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Dr. Mario (JP) (stylized as D℞. Mario) is a game released to the Nintendo Entertainment System and Game Boy in 1990 and 1991 and was later re-released on the Game Boy Advance in 2004 and 2005. It also made it's way on to the Virtual Console for the Nintendo 3DS and Wii U in 2012 and 2014, respectively.


It is a puzzle game where the objective is to defeat different colored germs using vitamins of the same color. It is basically four in a row just like Tetris (row or column counts) or to put it another way, to defeat each germ, three halves of the same color must be next to the germ. These halves do not need to be on the same pill. The germs will multiply as the levels progress.

The germs come in three colors: red, yellow, and blue. The red and blue ones are named Fever and Chill (respectively), after the two music tracks provided, while the yellow one is named Weird.