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Dr. Mario (Dr. マリオ Dokutā Mario) is Mario, as a doctor, who stars in a series of puzzle games, and is also a playable character in Super Smash Bros. Melee.
- Dr. Mario (Game Boy) - Released on the Nintendo Game Boy
- Dr. Mario (NES) - Released on the Nintendo Entertainment System
- Tetris & Dr. Mario - Released on the Super Nintendo Entertainment System
- Dr. Mario BS - Released on the Super Famicom add on Satellaview
- Dr. Mario 64 - Released on the Nintendo 64
- Classic NES Series: Dr. Mario - Released on the Nintendo Game Boy Advance
- Dr. Mario / Puzzle League - Released on the Nintendo Game Boy Advance