Dr. Mario & Puzzle League is a game released for the Game Boy Advance in 2005 by Nintendo and Intelligent Systems. The game is a compilation of Dr. Mario and Panel de Pon (known as Puzzle League in this game). The game was released alongside the Game Boy Micro's release in Japan, and the 20th anniversary of Super Mario Bros.
Dr. Mario
Dr. Mario in this game is more akin to Dr. Mario 64 then other versions of the game. There is a mode you unlock that has you turn the GBA so that the screen is longer vertically. In order to get this mode, you must complete level 20 in single player. When the player downloads a version of the game to another Game Boy Advance system, they'll be given NES style graphics and sound.
Puzzle League
Puzzle League is a remake of the games Panel de Pon, Tetris Attack, and Pokémon Puzzle League. It isn't similar to any of the the three games, but its appearance can be attributed to the GBA download version from Nintendo Puzzle Collection. Like Dr. Mario, a vertical version of the game is present where you tilt your GBA. In order to get this mode, you must score a total of 10,000 points or more in the game's endless mode.