Medusa

Medusa is the main villain of the Kid Icarus series. She first appeared in the original Kid Icarus, and will return along with the rest of the cast in the Nintendo 3DS game Kid Icarus: Uprising. Much like Palutena was based on the Greek goddess Pallas Athena, Medusa is based on the mythological character with the same name. The relation between the two characters also derives from the myths, where Athena transformed her into her monstrous shape.

Kid Icarus
Medusa, along with Palutena, was the co-ruler of the kingdom Angel Land. Medusa however, hated mortals and used the power of darkness to destroy their crops and turn them into stone. When Palutena found out about Medusa's doings she turned her into a hideous monster and banishes her to the Underworld. Medusa did not want to stay with her arms crossed, so she decided to take revenge on Palutena. Medusa joined forces with evil spirits and monsters in the underworld and managed to subdue Palutena's army. She banished Palutena and gave the Three Sacred Treasures to her most trusted monsters for protection.

In a last effort to regain the power of the land, Palutena used her last power to free the angel Pit from his prison and to grant him with a sacred bow. Using this he set out on an quest to retrieve the three treasure and using these he was able to defeat Medusa once and for all.

Kid Icarus: Uprising
After missing out on the second game in the series, Kid Icarus: Of Myths and Monsters, Medusa will return in Uprising for Nintendo 3DS. At this time little is known about the story except for the fact that Medusa is reborn and that she uses her army to attack the Angel Land.